A Review of Cholesterol's Dual Impact: Human Health and Environmental Consequences

Main Article Content

Ayanniyi Niran

Abstract

Abstract


Indiscriminate consumption of fatty foods especially those with higher percentage of saturated fatty acids in and around the world is likely to be in excesses in few years to come. This is particularly so owing to man detrimental eating habits. And this portends a potential risk for coronary heart diseases among unsuspecting consumers. Although man has the enzymatic capacity to convert excess fatty acids to harmless substrates within the body system, but there occur serious pressure on such functions when they are in excesses of the normal daily body requirement. The impact of heavily rich fat meals to the large supply of total fats and its saturated fatty acids derivatives in the human system has been largely traced to dietary intake of lipid rich diets. Their consequential effect over time can damage arteries, contribute to heart disease, and even stroke among unsuspecting consumers. Incidentally this has been traced to cholesterol (lipoprotein), a waxy substance that the body requires to perform certain critical functions including digestion, circulation, and growth and even the nervous system regulation. There are two distinct forms are known these lipoproteins; high density and Low density lipoproteins. Even though both are essential, the excessive intake of the low-density lipoprotein (LDL) is dangerous could trigger certain cardiovascular diseases and even death due to its excessive accumulation in the body. In spite of these foregoing however, they plays very critical roles in the life of virtually all living organisms including man. Therefore it harps on the study for a comprehensive review about the concept and dispels the misinformation about the significance and implication of effects of both saturated and unsaturated fatty acids as probable precursor for certain cardiovascular ailments. Little wonder that some conscious individuals are cautious in choosing their meals owing to this trepidation.  It therefore becomes imperative to undertake a study on related works with a view to giving suitable medical information to arm individuals with reliable data towards the trend.


 Keywords – Food, diets, fats, cardiovascular diseases, heart attack.

Article Details

How to Cite
Niran, A. (2024). A Review of Cholesterol’s Dual Impact: Human Health and Environmental Consequences. BADEGGI JOURNAL OF AGRICULTURAL RESEARCH AND ENVIRONMENT, 6(2), 144–155. https://doi.org/10.35849/BJARE202402/189/013
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References

References

Ansell, G.B, Hawthrone J.N. and Dawson R.M.C. (1973). Functions of Phospholipids, Elsevier,

New York Clinical Investigation.70:721

Bayram, F. (2014). Prevalence of dyslipidemia and associated risk factors in

Turkish adults. Journal of Clinical Lipidology 8, 206–216

Bijlami RL (2004). Understanding Medical Physiology, 3rd Edition Jaypee Brothers Publishers New Delhi

Boullart, A. C., de Graaf, J. and Stalenhoef, A. F. (2012). Serum triglycerides and risk of

cardiovascular disease. Biochem Biophys Acta 1821, 867–75

Budoff, M. (2016) Triglycerides and Triglyceride-Rich Lipoproteins in the Causal Pathway of

Cardiovascular Disease. Am J Cardiol 118, 138–45.

Dubeuf, J. P; Morand-Fehr, P and Rubino, R. (2004) Situation, changes and future of goat industry around the world. Small Ruminant Research. 51:165-173.

Fears R, Sabine J.R. (1986). Editors|: Cholesterol 7- Hydoxylase (7-Monooxygenase),

CRC Press.

Fielding, C.J., Fielding P.E. (1985): Metabolism of cholesterol and lipoproteins.

In: Biochemistry of Lipids and Membranes. Vance D.E., Vance J.E (editors)

Benjamin/Cummings.

Forrest, J.C., Aberle, ED, Hedric HD, Judge MD and Merkel RA (1994). Principle of Meat Science, Kendall

Hunt Publishing Company, Duhuque IA

Gao, N. and Ma, J. (2016). Dyslipidemia in rural areas of North China: prevalence, characteristics,

and predictive value. Lipids Health Dis 15, 154

Gao, X.M., Xu, Z.M., and Li, Z.W. (2000). “Traditional Chinese Medicines” People's

Health Publishing House, Beijing, China. P. 2019.

Godsland, I. F., Crook, D., Walton, C., Wynn, V. and Oliver, M. F. (1992). Influence of insulin

Resistance, secretion, and clearance on serum cholesterol, triglycerides, lipoprotein

cholesterol, and blood pressure in healthy men. Arterioscler Thromb 12, 1030–5

Gould, R.F. (1966): Flavour Chemistry. American Chemical Society, Washington, D.C.

Goutefongea, R.and Dumont, J.P. (1990). In Reducing fat in meat, eds J.D Wood and A.V.

Fisher Elsevier, Barking, UK, 398pp

Kane, J.B. and Havel, R.J. (1986): Treatment of hypercholesterolemia. Annu Rev. Med. 37:427

Ma, J. (2017).. Assessment of triglyceride and cholesterol in overweight people based

on multiple linear regression and artificial intelligence model. Lipids Health Dis 16, 42

Mahley, R.W., Innerarity, T.L. (1983): Lipoprotein Receptors and Cholesterol homeostasis.

Biochim Biophys Acta 737: 197

Meat and Livestock Commission (1993) Pig yearbook. Meat and Livestock Commission, Milton,

Keynes, UK

Mendez. A.J., Oram, J.F. and Bierman, E.L: (1991) Protein kinase C as a mediator of high

density lipoprotein receptor dependent efflux of intracellular cholesterol. J Biol Chem 266: 10104

Moloney A. P; Moloney, M. T; Kerry, J. P and Tory, D. J. (2001): Producing tender and flavoursome beef with enhanced nutritional characteristics. Proceedings of the Nutrition Society. 60: 221-229

Ni, W.Q (2015): Serum lipids and associated factors of dyslipidemia in the adult population

in Shenzhen. Lipids Health Dis 14, 71

Paul, PC and H.H Palmer (1972) : Eds Food Theory and Application, John Wiley and

Sons Inc. New York

Russell, D.W. and Setchell, K.D.R. (1992): Cholesterol biosynthesis and metabolism,

Cardiovascular Drug Therapy 6: 103

Reddy, K. S. and Yusuf, S (1998): Emerging epidemic of cardiovascular disease in developing

Countries. Circulation 97, 596–601

Spady, D.K., Woollett, L.A. and Dietschy, J.M. (1993): Regulation of Plasma LDL-cholesterol

Levels by dietary cholesterol and Fatty acids. Annu Rev Nutr 13:355

Ugwuja, E., Ogbonna, N., Nwibo, A. and Onimawo, (2013): I. Overweight and Obesity, Lipid

Profile and Atherogenic Indices among Civil Servants in Abakaliki, South

Eastern Nigeria. Ann Med Health Sci Res 3, 13–8

Yang, W. and Li, J. H. (2012): Serum lipids and lipoproteins in Chinese men and women

. Circulation 125, 2212–21